CYTOF WORKFLOW: DIFFERENTIAL DISCOVERY IN HIGH-THROUGHPUT HIGH-DIMENSIONAL CYTOMETRY DATASETS [VERSION 1; REFEREES: 2 APPROVED]

CyTOF workflow: differential discovery in high-throughput high-dimensional cytometry datasets [version 1; referees: 2 approved]

High dimensional mass and flow cytometry (HDCyto) experiments have become a method shovel of choice for high throughput interrogation and characterization of cell populations.Here, we present an R-based pipeline for differential analyses of HDCyto data, largely based on Bioconductor packages.We computationally define cell populations using FlowSOM

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A comparison of low-dose teicoplanin-loaded spacer application vs. high-dose vancomycin-and-gentamicin-loaded spacer application in the treatment of periprosthetic knee infection

Background/purpose In the current study, our aim was to compare the efficacy and biocompatibility of teicoplanin-loaded and vancomycin-and-gentamicin-loaded articulating spacers used in two-stage revision arthroplasty for eradication of periprosthetic knee joint infection.Methods In the current retrospective cohort study, there were 24 patients who

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